Structure of PDB 7tut Chain j

Receptor sequence

>7tutj (length=86) Species: 9986 (Oryctolagus cuniculus)

TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSA
KAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPK

3D structure

• PDB: 7tut Mechanism of an intramembrane chaperone for multipass membrane proteins.
• Chain: j
• Resolution: 3.88 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	j	R20 R21 C22 G23 T59 G62 R63 M64 R65 H66 L67 K68 R72 R73 F74 H76 R79 T82 P84 K87	R19 R20 C21 G22 T58 G61 R62 M63 R64 H65 L66 K67 R71 R72 F73 H75 R78 T81 P83 K86
BS02	rna	j	T2 K3 G4 T5 S6 S7 F8 G9 K10 R11 R12 N13 K14 T15 H16 K25 H28 Q30 K31 G35 R43 K44 R45 K46 Y47 N48 W49 K52 A53 R55 R56 Y71 E80 G81	T1 K2 G3 T4 S5 S6 F7 G8 K9 R10 R11 N12 K13 T14 H15 K24 H27 Q29 K30 G34 R42 K43 R44 K45 Y46 N47 W48 K51 A52 R54 R55 Y70 E79 G80
BS03	ZN	j	C19 C34	C18 C33

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7tut, PDBe:7tut, PDBj:7tut
• PDBsum: 7tut
• PubMed: 36261528
• UniProt: U3KPD5|RL37_RABIT Large ribosomal subunit protein eL37 (Gene Name=RPL37)