Structure of PDB 7qwq Chain j

Receptor sequence

>7qwqj (length=86) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSA
KAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPK

3D structure

PDB

7qwq Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting.

Chain

Resolution

2.83 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	j	T2 K3 G4 T5 S6 S7 F8 G9 K10 R11 R12 N13 K14 T15 H16 K25 H28 Q30 K36 R43 K44 R45 K46 Y47 N48 W49 K52 R55 R56 T59 Y71 R75 E80 G81	T1 K2 G3 T4 S5 S6 F7 G8 K9 R10 R11 N12 K13 T14 H15 K24 H27 Q29 K35 R42 K43 R44 K45 Y46 N47 W48 K51 R54 R55 T58 Y70 R74 E79 G80
BS02	rna	j	R20 R21 K42 T59 G62 R63 M64 H66 Y71 R72 F74 R79 E80 G81 T82 P84 K85 K87	R19 R20 K41 T58 G61 R62 M63 H65 Y70 R71 F73 R78 E79 G80 T81 P83 K84 K86
BS03	ZN	j	C19 C22 C34 C37	C18 C21 C33 C36

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding
GO:0046872	metal ion binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:7qwq, PDBe:7qwq, PDBj:7qwq
PDBsum	7qwq
PubMed	35201867
UniProt	U3KPD5\|RL37_RABIT Large ribosomal subunit protein eL37 (Gene Name=RPL37)