Structure of PDB 7ohv Chain j

Receptor sequence

>7ohvj (length=73) Species: 559292 (Saccharomyces cerevisiae S288C)

KSHTLCNRCGRRSFHVQKKTCSSCGYPAAKTRSYNWGAKAKRRHTTGTGR
MRYLKHVSRRFKNGFQTGSASKA

3D structure

• PDB: 7ohv Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
• Chain: j
• Resolution: 3.9 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	j	H16 R24 R25 H28 K31 S35 S36 A42 K43 T44 R45 Y47 N48 W49 K52 A53 R55 R56	H3 R11 R12 H15 K18 S22 S23 A29 K30 T31 R32 Y34 N35 W36 K39 A40 R42 R43
BS02	rna	j	R21 C22 G23 T59 G62 R63 M64 R65 Y66 K68 V70 R72 F74 N76 F78 Q79 T80 G81 A83 K85	R8 C9 G10 T46 G49 R50 M51 R52 Y53 K55 V57 R59 F61 N63 F65 Q66 T67 G68 A70 K72
BS03	ZN	j	C19 C22 C34 C37	C6 C9 C21 C24

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0008270 zinc ion binding
• GO:0019843 rRNA binding
• GO:0046872 metal ion binding

Biological Process

• GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:0030687 preribosome, large subunit precursor
• GO:0044391 ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7ohv, PDBe:7ohv, PDBj:7ohv
• PDBsum: 7ohv
• PubMed: 34813592
• UniProt: P49166|RL37A_YEAST Large ribosomal subunit protein eL37A (Gene Name=RPL37A)