Structure of PDB 6gq1 Chain j

Receptor sequence

>6gq1j (length=87) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]

GKGTPSFGKRHNKSHTLCNRCGRRSFHVQKKTCSSCGYPAAKTRSYNWGA
KAKRRHTTGTGRMRYLKHVSRRFKNGFQTGSASKASA

3D structure

PDB

6gq1 Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.

Chain

Resolution

4.4 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	j	G2 K3 G4 T5 P6 F8 G9 R11 H12 N13 K14 H16 R24 R25 S26 H28 Q30 K31 S35 K43 T44 R45 Y47 N48 W49 K52 R55 R56 K75	G1 K2 G3 T4 P5 F7 G8 R10 H11 N12 K13 H15 R23 R24 S25 H27 Q29 K30 S34 K42 T43 R44 Y46 N47 W48 K51 R54 R55 K74
BS02	rna	j	T17 R21 C22 G23 V29 G60 T61 R63 M64 Y66 R72 F74 N76 Q79 T80 A83 K85 A88	T16 R20 C21 G22 V28 G59 T60 R62 M63 Y65 R71 F73 N75 Q78 T79 A82 K84 A87
BS03	ZN	j	C19 C34 C37	C18 C33 C36

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0008270	zinc ion binding
GO:0019843	rRNA binding
GO:0046872	metal ion binding

	Biological Process
GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0030687	preribosome, large subunit precursor
GO:0044391	ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:6gq1, PDBe:6gq1, PDBj:6gq1
PDBsum	6gq1
PubMed	29886014
UniProt	P49166\|RL37A_YEAST Large ribosomal subunit protein eL37A (Gene Name=RPL37A)