Structure of PDB 5xtc Chain j

Receptor sequence
>5xtcj (length=115) Species: 9606 (Homo sapiens) [Search protein sequence]
MNFALILMTNTLLALLLMIITFWLPQLNGYMEKSTPYECGFDPMSPARVP
FSMKFFLVAITFLLFDLEIALLLPLPWALQTTNLPLMVMSSLLLIIILAL
SLAYEWLQKGLDWAE
3D structure
PDB5xtc Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Chainj
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLX j W106 L107 W106 L107
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0006979 response to oxidative stress
GO:0009060 aerobic respiration
GO:0009642 response to light intensity
GO:0009725 response to hormone
GO:0042776 proton motive force-driven mitochondrial ATP synthesis
GO:0071385 cellular response to glucocorticoid stimulus
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045271 respiratory chain complex I

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5xtc, PDBe:5xtc, PDBj:5xtc
PDBsum5xtc
PubMed28844695
UniProtP03897|NU3M_HUMAN NADH-ubiquinone oxidoreductase chain 3 (Gene Name=MT-ND3)

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