Structure of PDB 8cku Chain i

Receptor sequence

>8ckui (length=199) Species: 4932 (Saccharomyces cerevisiae)

FTPVVLATPIPEEVQQAQTEIKLFNKWSFEEVEVKDASLVDYVQVRQPIF
VAHTAGRYANKRFRKAQCPIIERLTNSLMMNGRNNGKKLKAVRIIKHTLD
IINVLTDQNPIQVVVDAITNTGPREDTTRVRQAVDVSPLRRVNQAIALLT
IGAREAAFRNIKTIAETLAEELINAAKGSSTSYAIKKKDELERVAKSNR

3D structure

• PDB: 8cku mRNA reading frame maintenance during eukaryotic ribosome translocation
• Chain: i
• Resolution: 3.11 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	i	H72 Y77 A78 K80 R81 K84 R92 N95 M98 N100 G101 R102 N103 N104 K106 K107 L108 K109 R112 N169 R180 N186 I187 T189 I190	H53 Y58 A59 K61 R62 K65 R73 N76 M79 N81 G82 R83 N84 N85 K87 K88 L89 K90 R93 N143 R154 N160 I161 T163 I164

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003729 mRNA binding
• GO:0003735 structural constituent of ribosome
• GO:0005515 protein binding
• GO:0019843 rRNA binding

Biological Process

• GO:0000028 ribosomal small subunit assembly
• GO:0000054 ribosomal subunit export from nucleus
• GO:0002181 cytoplasmic translation
• GO:0006412 translation
• GO:0006450 regulation of translational fidelity
• GO:0030490 maturation of SSU-rRNA

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:0022627 cytosolic small ribosomal subunit
• GO:0030686 90S preribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8cku, PDBe:8cku, PDBj:8cku
• PDBsum: 8cku
• PubMed: 38030725
• UniProt: P26783|RS5_YEAST Small ribosomal subunit protein uS7 (Gene Name=RPS5)