Structure of PDB 7w0y Chain i

Receptor sequence
>7w0yi (length=347) Species: 9823 (Sus scrofa) [Search protein sequence]
MNPIIYTTLIMTVMSGTMLVMISSHWLLIWIGFEMNLLAMIPVLMKNFNP
RATEAATKYFLTQATASMMLMMAIIINLLYSGQWTITKMFNPVAMTMMTM
ALAMKLGLSPFHFWVPEVTQGISLQAGLLLLTWQKLAPLSVLCQISQSIN
PNLMLTMAMLSILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNTTM
TILNLLIYITMTLAMFMLLIHSSATTTLSLSHTWNKMPVITSLMMVTLLS
MGGLPPLSGFMPKWMIIQEMTKNESIIMPTLMAMTALLNLYFYMRLAYSS
SLTMFPSTNNMKMKWQFEHTKQMKLLPTMIVLSTLVLPMTPALSSLN
3D structure
PDB7w0y The coupling mechanism of mammalian mitochondrial complex I.
Chaini
Resolution3.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLX i L203 L332 M339 L343 L346 L203 L332 M339 L343 L346
Gene Ontology
Molecular Function
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:0072593 reactive oxygen species metabolic process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045271 respiratory chain complex I

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7w0y, PDBe:7w0y, PDBj:7w0y
PDBsum7w0y
PubMed35145322
UniProtO79875|NU2M_PIG NADH-ubiquinone oxidoreductase chain 2 (Gene Name=MT-ND2)

[Back to BioLiP]