Structure of PDB 7v2d Chain i

Receptor sequence
>7v2di (length=347) Species: 9823 (Sus scrofa) [Search protein sequence]
MNPIIYTTLIMTVMSGTMLVMISSHWLLIWIGFEMNLLAMIPVLMKNFNP
RATEAATKYFLTQATASMMLMMAIIINLLYSGQWTITKMFNPVAMTMMTM
ALAMKLGLSPFHFWVPEVTQGISLQAGLLLLTWQKLAPLSVLCQISQSIN
PNLMLTMAMLSILIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLPYNTTM
TILNLLIYITMTLAMFMLLIHSSATTTLSLSHTWNKMPVITSLMMVTLLS
MGGLPPLSGFMPKWMIIQEMTKNESIIMPTLMAMTALLNLYFYMRLAYSS
SLTMFPSTNNMKMKWQFEHTKQMKLLPTMIVLSTLVLPMTPALSSLN
3D structure
PDB7v2d The coupling mechanism of mammalian mitochondrial complex I.
Chaini
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLX i L203 I207 L332 M339 A342 N347 L203 I207 L332 M339 A342 N347
Gene Ontology
Molecular Function
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:0072593 reactive oxygen species metabolic process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045271 respiratory chain complex I

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7v2d, PDBe:7v2d, PDBj:7v2d
PDBsum7v2d
PubMed35145322
UniProtO79875|NU2M_PIG NADH-ubiquinone oxidoreductase chain 2 (Gene Name=MT-ND2)

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