Structure of PDB 6zon Chain i

Receptor sequence
>6zoni (length=125) Species: 9606 (Homo sapiens) [Search protein sequence]
NVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAM
LAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMK
IGRIEDVTPIPSDSTRRKGGRRGRR
3D structure
PDB6zon Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Chaini
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna i N38 D39 F41 H43 G49 E51 T52 R55 T57 G59 D65 R66 E68 R104 I135 P136 S137 D138 T140 R141 K143 R146 R147 R149 R150 N13 D14 F16 H18 G24 E26 T27 R30 T32 G34 D40 R41 E43 R79 I110 P111 S112 D113 T115 R116 K118 R121 R122 R124 R125
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0045182 translation regulator activity
GO:0048027 mRNA 5'-UTR binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0006417 regulation of translation
GO:0030218 erythrocyte differentiation
GO:0030490 maturation of SSU-rRNA
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0014069 postsynaptic density
GO:0015935 small ribosomal subunit
GO:0016020 membrane
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0032040 small-subunit processome
GO:0045202 synapse
GO:0070062 extracellular exosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zon, PDBe:6zon, PDBj:6zon
PDBsum6zon
PubMed32680882
UniProtP62263|RS14_HUMAN Small ribosomal subunit protein uS11 (Gene Name=RPS14)

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