Structure of PDB 6gsm Chain i

Receptor sequence

>6gsmi (length=95) Species: 559292 (Saccharomyces cerevisiae S288C)

GPKRELIYKEEGQEYAQITKMLGNGRVEASCFDGNKRMAHIRGKLRKKVW
MGQGDIILVSLRDFQDDQCDVVHKYNLDEARTLKNQGELPENAKI

3D structure

• PDB: 6gsm Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
• Chain: i
• Resolution: 5.15 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	i	L42 G43 N44 R46 I61 R62 G63 K64 L65 R66 V69 M71	L22 G23 N24 R26 I41 R42 G43 K44 L45 R46 V49 M51

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003743 translation initiation factor activity

Biological Process

• GO:0006413 translational initiation

External links

• PDB: RCSB:6gsm, PDBe:6gsm, PDBj:6gsm
• PDBsum: 6gsm
• PubMed: 34648019
• UniProt: P38912|IF1A_YEAST Eukaryotic translation initiation factor 1A (Gene Name=TIF11)