Structure of PDB 5tbw Chain i

Receptor sequence

>5tbwi (length=159) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]

GNDVEDADVVVLPPKEIVKSNTSSKKADVPPPSADPSKARKNRPRPSGNE
GAIRDKTAGRRNNRSKDVTDSATTKKSNTRRATDRHSRTGKTDTKKKVNQ
GWGDDKKELSAEKEAQADAAAEIAELAAEAEDALQDYLNQQANNQFNKVP
EAKKVELDA

3D structure

PDB

5tbw Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides.

Chain

Resolution

3.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	i	K27 T30 S31 S32 K33 K34 A42 D43 P44 K46 A47 R48 K49	K19 T22 S23 S24 K25 K26 A34 D35 P36 K38 A39 R40 K41
BS02	rna	i	R68 N71 R72 V76 A80 K84 A90 D92 R93 H94 S95 R96 K99 T100 T102 K104 Q108 K115	R60 N63 R64 V68 A72 K76 A82 D84 R85 H86 S87 R88 K91 T92 T94 K96 Q100 K107
BS03	MG	i	N29 S31	N21 S23

External links

PDB	RCSB:5tbw, PDBe:5tbw, PDBj:5tbw
PDBsum	5tbw
PubMed	29064494
UniProt	P39015\|STM1_YEAST Suppressor protein STM1 (Gene Name=STM1)

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