Structure of PDB 8cre Chain h

Receptor sequence

>8creh (length=70) Species: 5476 (Candida albicans) [Search protein sequence]

RKKKVYTTPKKIKHKHRKHKLAVLTYYKVDNEGNVERLRRECPAPTCGAG
IFMANMKDRQYCGKCHLTLK

3D structure

PDB

8cre Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement

Chain

Resolution

3.0 Å

3D
structure

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	h	K125 Y127 T128 T129 K131 K132 K134 H135 K136 K139 K141 L142 Y147 R160 I172 F173 M174 A175 M177 R180 Y182 C183 G184 K185 H187 T189	K4 Y6 T7 T8 K10 K11 K13 H14 K15 K18 K20 L21 Y26 R39 I51 F52 M53 A54 M56 R59 Y61 C62 G63 K64 H66 T68
BS02	ZN	h	C163 C168 C186	C42 C47 C65

External links

PDB	RCSB:8cre, PDBe:8cre, PDBj:8cre
PDBsum	8cre
PubMed
UniProt	Q5A109\|RS31_CANAL Ubiquitin-ribosomal protein eS31 fusion protein (Gene Name=UBI3)