Structure of PDB 7ut1 Chain h

Receptor sequence
>7ut1h (length=231) Species: 11757 (Mouse mammary tumor virus) [Search protein sequence]
LESAQESHALHHQNAAALRFQFHITREQAREIVKLCPNCPLKPRVLWQMD
VTHVSEFGKLKYVHVTVDTYSHFTFATARTGEATKDVLQHLAQSFAYMGI
PQKIKTDNAPAYVSRSIQEFLARWKISHVQAIVERTHQNIKAQLNKLQKY
YTPHHLLAHALFVLNHVNMDNQGHTAAERHWGPMVMWKDLLTGSWKGPDV
LITAGRGYACVFPQDAESPIWVPDRFIRPFT
3D structure
PDB7ut1 B-to-A transition in target DNA during retroviral integration.
Chainh
Resolution3.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna h R240 W255 R259 R206 W221 R225
BS02 ZN h H9 H13 C37 C40 H8 H12 C36 C39
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7ut1, PDBe:7ut1, PDBj:7ut1
PDBsum7ut1
PubMed35947647
UniProtP03365|POL_MMTVB Gag-Pro-Pol polyprotein (Gene Name=gag-pro-pol)

[Back to BioLiP]