Structure of PDB 7tnq Chain h

Receptor sequence
>7tnqh (length=201) Species: 508771 (Toxoplasma gondii ME49) [Search protein sequence]
SQPVFASPLNVEKRRLNEERALMQAQKANIQLPPNYGDMDLILFPEGSLK
NSNNTVIPQSHLKGKSVALYFADGADPKCASLLPFLLNYYRTMNEGGANQ
KIEIIFVSLDRDREAFESHRAHMPWLSIDLENPLTEILKRHFRVMKEYEV
PTYGYGSRTGVPSVIVIGSDGREAQFLPICSGLEEGDRALLRWDWRNTKF
A
3D structure
PDB7tnq Cryo-ET of Toxoplasma parasites gives subnanometer insight into tubulin-based structures.
Chainh
Resolution8.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.8.1.8: protein-disulfide reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide h Q3 Y154 Q2 Y148
BS02 peptide h E101 G102 E95 G96
Gene Ontology
Molecular Function
GO:0004791 thioredoxin-disulfide reductase (NADPH) activity
GO:0016491 oxidoreductase activity
GO:0047134 protein-disulfide reductase (NAD(P)H) activity
Biological Process
GO:0030178 negative regulation of Wnt signaling pathway
GO:0031397 negative regulation of protein ubiquitination
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7tnq, PDBe:7tnq, PDBj:7tnq
PDBsum7tnq
PubMed35121661
UniProtA0A125YMM3

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