Structure of PDB 7r42 Chain h

Receptor sequence
>7r42h (length=138) Species: 9913 (Bos taurus) [Search protein sequence]
KRLFIIKPSGFYDKRFLKLLRFYILLTGIPVAIGITLINVFIGEAELAEI
PEGYVPEHWEYFKHPISRWIARTFFDGPEKNYERTMAILQIEAEKAELRL
KELEVRRLMRARGDGPWFHYPTIDKELIDHSPKATPDN
3D structure
PDB7r42 Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Chainh
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 I49 h R111 W122 F123 R106 W117 F118
Gene Ontology
Biological Process
GO:0032981 mitochondrial respiratory chain complex I assembly
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045271 respiratory chain complex I

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Biological Process
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Cellular Component
External links
PDB RCSB:7r42, PDBe:7r42, PDBj:7r42
PDBsum7r42
PubMed36701435
UniProtQ02380|NDUB5_BOVIN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (Gene Name=NDUFB5)

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