Structure of PDB 7pex Chain h

Receptor sequence
>7pexh (length=95) Species: 9606 (Homo sapiens) [Search protein sequence]
KRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASR
LAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA
3D structure
PDB7pex Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory.
Chainh
Resolution5.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna h S32 R33 I54 S55 S56 R86 S87 T88 S3 R4 I25 S26 S27 R57 S58 T59
BS02 dna h R31 R33 S36 V39 Y40 R2 R4 S7 V10 Y11
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0002227 innate immune response in mucosa
GO:0019731 antibacterial humoral response
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
Cellular Component
GO:0000786 nucleosome
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:7pex, PDBe:7pex, PDBj:7pex
PDBsum7pex
PubMed35581345
UniProtO60814|H2B1K_HUMAN Histone H2B type 1-K (Gene Name=H2BC12)

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