Structure of PDB 8ipx Chain g

Receptor sequence

>8ipxg (length=145) Species: 9606 (Homo sapiens) [Search protein sequence]

PPKAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYP
RKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQ
AVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII

3D structure

PDB

8ipx Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.

Chain

Resolution

4.3 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	g	K37 T45 R47 R48 K50 T51 R53 R55 R56 Q57 K59 Y60 R62 T83 E84 K89 N93 N105 K106 H107 N125 T126 I128 P130 K134 Y137	K26 T34 R36 R37 K39 T40 R42 R44 R45 Q46 K48 Y49 R51 T72 E73 K78 N82 N94 K95 H96 N114 T115 I117 P119 K123 Y126
BS02	rna	g	K30 V32 H33 T51 L52 R56 K63 P66 R67 R68 N69 K70 H107 Q108	K19 V21 H22 T40 L41 R45 K52 P55 R56 R57 N58 K59 H96 Q97

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0019843	rRNA binding
GO:0045296	cadherin binding
GO:1904841	TORC2 complex binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0022626	cytosolic ribosome
GO:0070062	extracellular exosome
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:8ipx, PDBe:8ipx, PDBj:8ipx
PDBsum	8ipx
PubMed	37491604
UniProt	P62750\|RL23A_HUMAN Large ribosomal subunit protein uL23 (Gene Name=RPL23A)