Structure of PDB 8ine Chain g

Receptor sequence

>8ineg (length=143) Species: 9606 (Homo sapiens) [Search protein sequence]

KAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRK
SAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAV
KKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII

3D structure

PDB

8ine Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.

Chain

Resolution

3.2 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	g	H33 H35 K37 T45 R47 R48 K50 T51 R53 R55 Q57 P58 K59 Y60 T83 K89 N93 N105 K106 H107 K123 N125 T126 I128 P130 K134 K135 Y137 R139	H20 H22 K24 T32 R34 R35 K37 T38 R40 R42 Q44 P45 K46 Y47 T70 K76 N80 N92 K93 H94 K110 N112 T113 I115 P117 K121 K122 Y124 R126
BS02	rna	g	V32 H33 K36 L52 R56 K63 P66 R67 K70 H107 Q108	V19 H20 K23 L39 R43 K50 P53 R54 K57 H94 Q95

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0019843	rRNA binding
GO:0045296	cadherin binding
GO:1904841	TORC2 complex binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0022626	cytosolic ribosome
GO:0070062	extracellular exosome
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:8ine, PDBe:8ine, PDBj:8ine
PDBsum	8ine
PubMed	37491604
UniProt	P62750\|RL23A_HUMAN Large ribosomal subunit protein uL23 (Gene Name=RPL23A)