Structure of PDB 8c5c Chain g

Receptor sequence
>8c5cg (length=429) Species: 9913 (Bos taurus) [Search protein sequence]
MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVY
YNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNN
WAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTL
LISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETY
CIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADL
RKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM
AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVK
TAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTG
EGMDEMEFTEAESNMNDLVSEYQQYQDAT
3D structure
PDB8c5c The mitotic role of adenomatous polyposis coli requires its bilateral interaction with tubulin and microtubules.
Chaing
Resolution5.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TA1 g V23 L215 H227 A231 S234 P272 L273 T274 R276 P358 R359 G360 L361 V23 L215 H227 A231 S234 P272 L273 T274 R276 P358 R359 G360 L361
BS02 GDP g Q11 C12 N99 S138 G140 G141 T143 V169 Y222 N226 Q11 C12 N99 S138 G140 G141 T143 V169 Y222 N226
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
Biological Process
GO:0007017 microtubule-based process
Cellular Component
GO:0005874 microtubule

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8c5c, PDBe:8c5c, PDBj:8c5c
PDBsum8c5c
PubMed36541084
UniProtA0A452DIL8

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