Structure of PDB 6lqm Chain g

Receptor sequence

>6lqmg (length=117) Species: 9606 (Homo sapiens) [Search protein sequence]

IRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKK
IEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVR
LAPDYDALDVANKIGII

3D structure

PDB

6lqm Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.

Chain

Resolution

3.09 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	g	P44 T45 R47 R48 P49 K50 T51 R53 R56 Q57 P58 K59 Y60 R62 T83 K89 N105 K106 N125 T126 L127 I128 P130 K134 K135 Y137 R139	P5 T6 R8 R9 P10 K11 T12 R14 R17 Q18 P19 K20 Y21 R23 T44 K50 N66 K67 N86 T87 L88 I89 P91 K95 K96 Y98 R100
BS02	rna	g	P49 T51 L52 R56 K63 R67 R68 N69 K70 H107 Q108	P10 T12 L13 R17 K24 R28 R29 N30 K31 H68 Q69

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0019843	rRNA binding
GO:0045296	cadherin binding
GO:1904841	TORC2 complex binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0022626	cytosolic ribosome
GO:0070062	extracellular exosome
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:6lqm, PDBe:6lqm, PDBj:6lqm
PDBsum	6lqm
PubMed	32669547
UniProt	P62750\|RL23A_HUMAN Large ribosomal subunit protein uL23 (Gene Name=RPL23A)