Structure of PDB 5vyc Chain f2

Receptor sequence

>5vycf2 (length=72) Species: 9606 (Homo sapiens)

KKRKKKSCTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECG
AGVFMASHFDRHYCGKCCLTYC

3D structure

• PDB: 5vyc Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1.
• Chain: f2
• Resolution: 6.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	f2	E110 K113 R116 L117 R118	E33 K36 R39 L40 R41
BS02	rna	f2	K78 R80 K82 T86 P88 K89 K90 K92 H93 R95 K96 K97 V98 K99 L100 K104 Y105 R118 V130 F131 Y140 G142 T147	K1 R3 K5 T9 P11 K12 K13 K15 H16 R18 K19 K20 V21 K22 L23 K27 Y28 R41 V53 F54 Y63 G65 T70
BS03	ZN	f2	C121 C141	C44 C64

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0046872 metal ion binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005634 nucleus
• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:5vyc, PDBe:5vyc, PDBj:5vyc
• PDBsum: 5vyc
• PubMed: 28723557
• UniProt: Q5RKT7