Structure of PDB 9c4g Chain f

Receptor sequence

>9c4gf (length=184) Species: 1747 (Cutibacterium acnes) [Search protein sequence]

AHEMPRLKKQYREQIRAAMQEEFGYRNPMLIPGLEKIVVNMGVGDAAHDS
KVMDGAIRDITAITGQKPQVTKARKSIAQFKLREGQPIGCHVTLRGDRMW
EFADRLLTLALPRIRDFRGLNSNQFDGKGNYTFGLSEQVMFLEIDQDKID
RIRGMDITFVTTAQTNEEGKALLKHLGFPFKAKD

3D structure

PDB

9c4g Mechanistic basis for the translation inhibition of Cutibacterium acnes by Clindamycin.

Chain

Resolution

2.53 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	f	K42 V44 N46 M47 G48 G50 T77 A79 R80 Q85 F86 I94 H97 Q130 F131 D132 K134 N136 T138 F139 G140 L141 G160 M161 D162	K36 V38 N40 M41 G42 G44 T71 A73 R74 Q79 F80 I88 H91 Q124 F125 D126 K128 N130 T132 F133 G134 L135 G154 M155 D156
BS02	rna	f	N33 P34 M35 L36 Q72 K73 Q75 V76 T99 R101	N27 P28 M29 L30 Q66 K67 Q69 V70 T93 R95

External links

PDB	RCSB:9c4g, PDBe:9c4g, PDBj:9c4g
PDBsum	9c4g
PubMed	39122144
UniProt	A0A3E2DDM1

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