Structure of PDB 9bkd Chain f

Receptor sequence

>9bkdf (length=142) Species: 9606 (Homo sapiens) [Search protein sequence]

VIPEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLT
KRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGL
DNKLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGRT

3D structure

PDB

9bkd Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit.

Chain

Resolution

2.6 Å

3D
structure

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	f	R24 K25 F28 K34 G35 V36 G37 R38 R39 Y40 W82 F83 N85 Q87 K88 L107 D110 H120 R121 R124 H125 R130 V131 R132 Q134 H135 T136 K137 T138 T139 G140 R141 R144 T145	R21 K22 F25 K31 G32 V33 G34 R35 R36 Y37 W79 F80 N82 Q84 K85 L104 D107 H117 R118 R121 H122 R127 V128 R129 Q131 H132 T133 K134 T135 T136 G137 R138 R141 T142
BS02	MG	f	T136 T139 G140	T133 T136 G137

External links

PDB	RCSB:9bkd, PDBe:9bkd, PDBj:9bkd
PDBsum	9bkd
PubMed	39117603
UniProt	P62269\|RS18_HUMAN Small ribosomal subunit protein uS13 (Gene Name=RPS18)