Structure of PDB 8g6x Chain f

Receptor sequence

>8g6xf (length=177) Species: 562 (Escherichia coli) [Search protein sequence]

AKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLD
NAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFE
RLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRG
LDITITTTAKSDEEGRALLAAFDFPFR

3D structure

PDB

8g6x Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.

Chain

Resolution

2.31 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	f	T35 N37 G39 G41 T68 R71 K72 F77 I79 I85 K88 S121 F122 D123 S129 M130 G131 G151 L152 D153 T155 T157	T34 N36 G38 G40 T67 R70 K71 F76 I78 I84 K87 S120 F121 D122 S128 M129 G130 G150 L151 D152 T154 T156
BS02	rna	f	S24 M26 Q27 Q63 K64 L66 K69 T90 R92	S23 M25 Q26 Q62 K63 L65 K68 T89 R91

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0008097	5S rRNA binding
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:8g6x, PDBe:8g6x, PDBj:8g6x
PDBsum	8g6x
PubMed	37396857
UniProt	P62399\|RL5_ECOLI Large ribosomal subunit protein uL5 (Gene Name=rplE)

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