Structure of PDB 7uif Chain f

Receptor sequence
>7uiff (length=169) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
MNVTPLDELQWKSPEWIQVFGLRTENVLDYFAESPFFDKTSNNQVIKMQR
QFSQLNPARRQILFKYPMYMQLEEELMKLDGTEYVLSSVREPDFWVIRKQ
RRTNNSGVGSAKGPEIIPLQDYYIIGANIYQTIFKIVQSRLMSTSYHLNS
TLESLYDLIEFQPSQGVHY
3D structure
PDB7uif Structural basis of a transcription pre-initiation complex on a divergent promoter.
Chainf
Resolution4.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide f L9 Q10 W11 K12 L9 Q10 W11 K12
Gene Ontology
Molecular Function
GO:0003712 transcription coregulator activity
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0032968 positive regulation of transcription elongation by RNA polymerase II
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051123 RNA polymerase II preinitiation complex assembly
GO:0060261 positive regulation of transcription initiation by RNA polymerase II
Cellular Component
GO:0005634 nucleus
GO:0016592 mediator complex
GO:0070847 core mediator complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7uif, PDBe:7uif, PDBj:7uif
PDBsum7uif
PubMed36731470
UniProtP38782|MED6_YEAST Mediator of RNA polymerase II transcription subunit 6 (Gene Name=MED6)

[Back to BioLiP]