Structure of PDB 7p3k Chain f

Receptor sequence

>7p3kf (length=177) Species: 83333 (Escherichia coli K-12)

AKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLD
NAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFE
RLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRG
LDITITTTAKSDEEGRALLAAFDFPFR

3D structure

• PDB: 7p3k Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide.
• Chain: f
• Resolution: 2.9 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	f	K33 N37 M38 G39 G41 T68 A70 R71 K72 V74 F77 I79 I85 K88 S121 D123 R125 N127 S129 M130 R133 G151 L152 D153 T155	K32 N36 M37 G38 G40 T67 A69 R70 K71 V73 F76 I78 I84 K87 S120 D122 R124 N126 S128 M129 R132 G150 L151 D152 T154
BS02	rna	f	S24 M26 Q27 Q63 K64 L66 K69 K88 V89 T90 R92	S23 M25 Q26 Q62 K63 L65 K68 K87 V88 T89 R91
BS03	rna	f	A75 R80	A74 R79

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0000027 ribosomal large subunit assembly
• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7p3k, PDBe:7p3k, PDBj:7p3k
• PDBsum: 7p3k
• PubMed: 34403461
• UniProt: P62399|RL5_ECOLI Large ribosomal subunit protein uL5 (Gene Name=rplE)