Structure of PDB 7osm Chain eEF2

Receptor sequence

>7osmeEF2 (length=842) Species: 4932 (Saccharomyces cerevisiae)

MVAFTVDQMRSLMDKVTNVRNMSVIAHVDHGKSTLTDSLVQRAGIISAAK
AGEARFTDTRKDEQERGITIKSTAISLYSEMSDEDVKEIKQKTDGNSFLI
NLIDSPGHVDFSSEVTAALRVTDGALVVVDTIEGVCVQTETVLRQALGER
IKPVVVINKVDRALLELQVSKEDLYQTFARTVESVNVIVSTYADEVLGDV
QVYPARGTVAFGSGLHGWAFTIRQFATRYAKKFGVDKAKMMDRLWGDSFF
NPKTKKWTNKDTDAEGKPLERAFNMFILDPIFRLFTAIMNFKKDEIPVLL
EKLEIVLKGDEKDLEGKALLKVVMRKFLPAADALLEMIVLHLPSPVTAQA
YRAEQLYEGPADDANCIAIKNCDPKADLMLYVSKMVPTSDKGRFYAFGRV
FAGTVKSGQKVRIQGPNYVPGKKDDLFIKAIQRVVLMMGRFVEPIDDCPA
GNIIGLVGIDQFLLKTGTLTTSETAHNMKVMKFSVSPVVQVAVEVKNAND
LPKLVEGLKRLSKSDPCVLTYMSESGEHIVAGTGELHLEICLQDLEHDHA
GVPLKISPPVVAYRETVESESSQTALSKSPNKHNRIYLKAEPIDEEVSLA
IENGIINPRDDFKARARIMADDYGWDVTDARKIWCFGPDGNGPNLVIDQT
KAVQYLHEIKDSVVAAFQWATKEGPIFGEEMRSVRVNILDVTLHADAIHR
GGGQIIPTMRRATYAGFLLADPKIQEPVFLVEIQCPEQAVGGIYSVLNKK
RGQVVSEEQRPGTPLFTVKAYLPVNESFGFTGELRQATGGQAFPQMVFDH
WSTLGSDPLDPTSKAGEIVLAARKRHGMKEEVPGWQEYYDKL

3D structure

• PDB: 7osm Accuracy mechanism of eukaryotic ribosome translocation.
• Chain: eEF2
• Resolution: 3.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	eEF2	H27 H108 V137 R162 L536 P580 E737 Y744 N748 K749 Q753 V754 V755 E757 Q786 G789 G790	H27 H108 V137 R162 L536 P580 E737 Y744 N748 K749 Q753 V754 V755 E757 Q786 G789 G790
BS02	rna	eEF2	D390 K391 R393 Q432 R433 R510 A652	D390 K391 R393 Q432 R433 R510 A652
BS03	rna	eEF2	K578 K582 H583 R585 D696 X699	K578 K582 H583 R585 D696 X699
BS04	MG	eEF2	S33 T69	S33 T69
BS05	MG	eEF2	D390 K391 G392	D390 K391 G392
BS06	MG	eEF2	G624 W625	G624 W625
BS07	GTP	eEF2	V28 D29 G31 K32 S33 T34 I68 T69 K159 D161 S213 L215	V28 D29 G31 K32 S33 T34 I68 T69 K159 D161 S213 L215

Gene Ontology

--> -->

UnboundLocalError

Python 3.6.8: /usr/bin/python3 Sun Dec 1 04:29:44 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1443                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1444         else:

=> 1445             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1446     

   1447     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '7osm', asym_id = 'eEF2', title = 'Accuracy mechanism of eukaryotic ribosome translocation.'

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='7osm', asym_id='eEF2', title='Accuracy mechanism of eukaryotic ribosome translocation.')

    839 

    840     if go:

=>  841         display_go(go,uniprot,pdbid,asym_id)

    842     return pubmed,uniprot

    843 

global display_go = <function display_go>, go = '0003924,0005525', uniprot = '', pdbid = '7osm', asym_id = 'eEF2'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003924,0005525', uniprot='', pdbid='7osm', asym_id='eEF2')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>