Structure of PDB 7qwr Chain e

Receptor sequence

>7qwre (length=128) Species: 9986 (Oryctolagus cuniculus)

AALRPLVKPKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKG
QILMPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAH
NVSSKNRKAIVERAAQLAIRVTNPNARL

3D structure

• PDB: 7qwr Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting.
• Chain: e
• Resolution: 2.9 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	e	R5 L7 V8 K9 K14 K15 R16 T17 K18 K19 F20 R22 H23 Q24 D26 R27 Y28 V29 K30 I31 N34 W35 R36 K37 R39 G40 I41 D42 N43 R44 R46 R47 R48 K50 G51 Q52 P56 N57 I58 G59 Y60 G61 S62 N63 K64 K65 H68 K76 E98 I99 A100 H101 N102 S104 N107 R108 N124 A127 R128	R4 L6 V7 K8 K13 K14 R15 T16 K17 K18 F19 R21 H22 Q23 D25 R26 Y27 V28 K29 I30 N33 W34 R35 K36 R38 G39 I40 D41 N42 R43 R45 R46 R47 K49 G50 Q51 P55 N56 I57 G58 Y59 G60 S61 N62 K63 K64 H67 K75 E97 I98 A99 H100 N101 S103 N106 R107 N123 A126 R127

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7qwr, PDBe:7qwr, PDBj:7qwr
• PDBsum: 7qwr
• PubMed: 35201867
• UniProt: G1TUN8|RL32_RABIT Large ribosomal subunit protein eL32 (Gene Name=RPL32)