Structure of PDB 6hhq Chain d3

Receptor sequence

>6hhqd3 (length=144) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]

GKGKPRGLNSARKLRVHRRNNRWAENNYKKRLLGTAFKSSPFGGSSHAKG
IVLEKLGIESKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDE
VLLAGFGRKGKAKGDIPGVRFKVVKVSGVSLLALWKEKKEKPRS

3D structure

PDB

6hhq Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome.

Chain

Resolution

3.1 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	d3	G2 K3 G4 K5 P6 R7 G8 N10 R13 K14 R19 R20 N22 R23 W24 A25 E26 K30 K31 R32 F38 K39 S46 S47 H48 A49 K50 K62 N65 S66 A67 I68 R69 K70 K78 P88 D90 G91 G106 G108 R109 K112 K114 G115 D116 I117 R121 K123 K126 S131 K139	G1 K2 G3 K4 P5 R6 G7 N9 R12 K13 R18 R19 N21 R22 W23 A24 E25 K29 K30 R31 F37 K38 S45 S46 H47 A48 K49 K61 N64 S65 A66 I67 R68 K69 K77 P87 D89 G90 G105 G107 R108 K111 K113 G114 D115 I116 R120 K122 K125 S130 K138
BS02	MG	d3	L103 G129	L102 G128

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006412	translation
GO:0006450	regulation of translational fidelity
GO:1990145	maintenance of translational fidelity

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:6hhq, PDBe:6hhq, PDBj:6hhq
PDBsum	6hhq
PubMed	30759226
UniProt	P0CX29\|RS23A_YEAST Small ribosomal subunit protein uS12A (Gene Name=RPS23A)