Structure of PDB 8she Chain d

Receptor sequence
>8shed (length=520) Species: 9606 (Homo sapiens) [Search protein sequence]
RGKGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDV
TITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLD
SCTKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVELSDRETLLNSAT
TSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTI
DDCELVEGLVLTQKVSNSGITRVEKAKIGLIQFCLSAPKTDMDNQIVVSD
YAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLN
KMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLN
GSGKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKK
RALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAEN
AGLNPISTVTELRNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSA
LTLATETVRSILKIDDVVNT
3D structure
PDB8she Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller structure
Chaind
Resolution2.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP d L52 G53 P54 G105 S108 N172 S173 G425 V508 L34 G35 P36 G87 S90 N154 S155 G407 V490
BS02 AF3 d D73 T106 K174 D407 D55 T88 K156 D389
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0044183 protein folding chaperone
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding
GO:0007339 binding of sperm to zona pellucida
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0050821 protein stabilization
GO:0051086 chaperone mediated protein folding independent of cofactor
GO:0061077 chaperone-mediated protein folding
GO:0090666 scaRNA localization to Cajal body
GO:1904871 positive regulation of protein localization to Cajal body
GO:1904874 positive regulation of telomerase RNA localization to Cajal body
Cellular Component
GO:0002199 zona pellucida receptor complex
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005832 chaperonin-containing T-complex
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0042470 melanosome
GO:0042995 cell projection
GO:0044297 cell body
GO:0070062 extracellular exosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8she, PDBe:8she, PDBj:8she
PDBsum8she
PubMed37852256
UniProtP50991|TCPD_HUMAN T-complex protein 1 subunit delta (Gene Name=CCT4)

[Back to BioLiP]