Structure of PDB 7yev Chain d

Receptor sequence
>7yevd (length=1087) Species: 538123 (Mammalian orthoreovirus 3) [Search protein sequence]
GYQCHVCSAVLFSPLDLDAHVASHGLHGNRHITEFISSWQNHPIVQVSAD
VENRKTAQLLHADTPRLVTWDAGLCTSFKIVPIVPAQVPQDVLAYTFFTS
SYAIQSPFPEAAVSRIVVHTRWASNVDFDRDSSVIMAPPTENNIHLFKQL
LNTETLSVRGANPLMFRANVLHMLLEFVLDNLYLNRHTGFSQDHTPFTEG
ANLRSLPGPDAEKWYSIMYPTRMGTPNVSKICNFVASCVRNRVGRFDRAQ
MMNGAMSEWVDVFETSDALTVSIRGRWMARLARMNINPTEIEWALTECAQ
GYVTVTSPYAPSVNRLMPYRISNAERQISQIIRVMNIGNNATVIQPVLQD
ISVLLQRISPLQIDPTIISNTMSTVSESTTQTLSPASSILGKLRPSNSDF
SSFRVALAGWLYNGVVTTVIDDSSYPKDGGSVTSLENLWDFFILALALPL
TTDPCAPVKAFMTLANMMVGFETIPMDNQIYTQSRRASAFSTPHTWPRCF
MNIQLISPIDAPILRQWAEIIHRYWPNPSQIRYGTPNVFGSANLFTPPEV
LLLPIDHQPANVTTPTLDFTNELTNWRARVCELMKNLVDNQRYQPGWTQS
LVSSMRGTLGKLKLIKSMTPMYLQQLAPVELAVIAPMLPFPPFQVPYVRL
DRDRVPTMVGVTRQSRDTITQPALSLSTTNTTVGVPLALDARAITVALLS
GKYPPDLVTNVWYADAIYPMYADTEVFSNLQRDVITCEAVQTLVTLVAQI
SETQYPVDRYLDWIPSLRASAATAATFAEWVNTSMKTAFDLSDMLLEPLL
SGDPRMTQLAIQYQQYNGRTFNVIPEMPGSVIADCVQLTAEVFNHEYNLF
GIARGDIIIGRVQSTHLWSPLAPPPDLVFDRDTPGVHIFGRDCRISFGMN
GAAPMIRDETGMMVPFEGNWIFPLALWQMNTRYFNQQFDAWIKTGELRIR
IEMGAYPYMLHYYDPRQYANAWNLTSAWLEEITPTSIPSVPFMVPISSDH
DISSAPAVQYIISTEYNDRSLFCTNSSSPQTIAGPDKHIPVERYNILTNP
DAPPTQIQLPEVVDLYNVVTRYAYETPPITAVVMGVP
3D structure
PDB7yev In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation.
Chaind
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN d C186 H199 H203 C7 H20 H24
Gene Ontology
Molecular Function
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006370 7-methylguanosine mRNA capping
Cellular Component
GO:0019028 viral capsid
GO:0039625 viral inner capsid

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7yev, PDBe:7yev, PDBj:7yev
PDBsum7yev
PubMed36469786
UniProtC9E874

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