Structure of PDB 7r4d Chain d

Receptor sequence
>7r4dd (length=112) Species: 9913 (Bos taurus) [Search protein sequence]
ATFQFLPDEARSLPPPKLTDPRLAFVGFLGYCSGLIDNAIRRRPVLLAGL
HRQLLYITSFVFVGYYLLKRQDYMYAVRDHDMFSYIKSHPEDFPEKDKKT
YGEVFEEFHPVR
3D structure
PDB7r4d Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Chaind
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 I49 d M82 Y83 R86 M74 Y75 R78
Gene Ontology
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0032981 mitochondrial respiratory chain complex I assembly
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045271 respiratory chain complex I

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Biological Process
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Cellular Component
External links
PDB RCSB:7r4d, PDBe:7r4d, PDBj:7r4d
PDBsum7r4d
PubMed36701435
UniProtQ02827|NDUC2_BOVIN NADH dehydrogenase [ubiquinone] 1 subunit C2 (Gene Name=NDUFC2)

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