Structure of PDB 7pia Chain d

Receptor sequence

>7piad (length=175) Species: 272634 (Mycoplasmoides pneumoniae M129)

NLKAHYQKTIAKELQKSFAFSSIMQVPRLEKIVINMGVGDAIRDSKFLES
ALNELHLISGQKPVATKAKNAISTYKLRAGQLIGCKVTLRGERMWAFLEK
LIYVALPRVRDFRGLSLKSFDGRGNYTIGIKEQIIFPEIVYDDIKRIRGF
DVTLVTSTNKDSEALALLRALNLPL

3D structure

• PDB: 7pia Visualizing translation dynamics at atomic detail inside a bacterial cell.
• Chain: d
• Resolution: 13.6 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	d	N37 G39 V40 G41 I44 T68 K71 N72 I74 T76 Y77 I85 K88 K120 S121 F122 D123 R125 T129 I130 G131 I132 K133 R148 I149 R150 G151 F152 D153	N35 G37 V38 G39 I42 T66 K69 N70 I72 T74 Y75 I83 K86 K118 S119 F120 D121 R123 T127 I128 G129 I130 K131 R146 I147 R148 G149 F150 D151
BS02	rna	d	K5 S23 S24 I25 M26 Q27 Q63 K64 V66 A67 T68 K88 T90 R92 R95	K3 S21 S22 I23 M24 Q25 Q61 K62 V64 A65 T66 K86 T88 R90 R93
BS03	rna	d	T76 R80	T74 R78

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7pia, PDBe:7pia, PDBj:7pia
• PDBsum: 7pia
• PubMed: 36171285
• UniProt: Q50306|RL5_MYCPN Large ribosomal subunit protein uL5 (Gene Name=rplE)