Structure of PDB 6zmw Chain d

Receptor sequence

>6zmwd (length=142) Species: 9606 (Homo sapiens) [Search protein sequence]

GVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENW
FYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARR
VLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKK

3D structure

PDB

6zmw Structure of a human 48Stranslational initiation complex.

Chain

Resolution

3.7 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	d	G3 V4 T5 K7 Q11 Q12 R16 W33 K41 K43 E44 L45 P47 Y48 R56 S59 R62 R67 G68 G71 V72 G73 S74 K77 I78 R82 R84 G86 V87 M88 P89 S90 H91 F92 S96 K97 S98 R101 R102 K115 G119 G120 P125 Q128 R129 D132 R133	G1 V2 T3 K5 Q9 Q10 R14 W31 K39 K41 E42 L43 P45 Y46 R54 S57 R60 R65 G66 G69 V70 G71 S72 K75 I76 R80 R82 G84 V85 M86 P87 S88 H89 F90 S94 K95 S96 R99 R100 K113 G117 G118 P123 Q126 R127 D130 R131
BS02	MG	d	G80 G81	G78 G79

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0017134	fibroblast growth factor binding
GO:0019901	protein kinase binding
GO:0042802	identical protein binding

	Biological Process
GO:0000028	ribosomal small subunit assembly
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181	cytoplasmic translation
GO:0002548	monocyte chemotaxis
GO:0006364	rRNA processing
GO:0006412	translation
GO:0007000	nucleolus organization
GO:0030218	erythrocyte differentiation
GO:0030490	maturation of SSU-rRNA
GO:0031640	killing of cells of another organism
GO:0042274	ribosomal small subunit biogenesis
GO:0050829	defense response to Gram-negative bacterium
GO:0060265	positive regulation of respiratory burst involved in inflammatory response
GO:0060266	negative regulation of respiratory burst involved in inflammatory response
GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide

	Cellular Component
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0005925	focal adhesion
GO:0014069	postsynaptic density
GO:0016020	membrane
GO:0022626	cytosolic ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:0032040	small-subunit processome
GO:0070062	extracellular exosome
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:6zmw, PDBe:6zmw, PDBj:6zmw
PDBsum	6zmw
PubMed	32883864
UniProt	P39019\|RS19_HUMAN Small ribosomal subunit protein eS19 (Gene Name=RPS19)