Structure of PDB 8ine Chain c

Receptor sequence

>8inec (length=155) Species: 9606 (Homo sapiens) [Search protein sequence]

TNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKG
MPHKCYHGKTGRVYNVTQHAVGIVVNKQVKGKILAKRINVRIEHIKHSKS
RDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPELL
EPIPY

3D structure

PDB

8ine Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.

Chain

Resolution

3.2 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	c	T2 N3 T4 K5 G6 K7 R8 R9 G10 R12 Y13 F19 H22 G23 K36 K43 Q49 K50 H54 K55 H58 G59 T61 T68 Q69 H70 K78 V80 K87 R88 R92 K100 S101 R102 F105 R108 V109 N112 W125 L128 K129 R130 P132 F140 R142	T1 N2 T3 K4 G5 K6 R7 R8 G9 R11 Y12 F18 H21 G22 K35 K42 Q48 K49 H53 K54 H57 G58 T60 T67 Q68 H69 K77 V79 K86 R87 R91 K99 S100 R101 F104 R107 V108 N111 W124 L127 K128 R129 P131 F139 R141
BS02	rna	c	R20 P26 A28	R19 P25 A27

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005829	cytosol
GO:0005840	ribosome
GO:0016020	membrane
GO:0022625	cytosolic large ribosomal subunit
GO:0022626	cytosolic ribosome
GO:0045202	synapse
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:8ine, PDBe:8ine, PDBj:8ine
PDBsum	8ine
PubMed	37491604
UniProt	P46778\|RL21_HUMAN Large ribosomal subunit protein eL21 (Gene Name=RPL21)

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