Structure of PDB 7yev Chain c

Receptor sequence
>7yevc (length=1082) Species: 538123 (Mammalian orthoreovirus 3) [Search protein sequence]
HGYQCHVCSAVLFSPLDLDAHVASHGLHGNRHITEFISSWQNHPIVQVSA
DVENRKTAQLLHADTPRLVTWDAGLCTSFKIVPIVPAQVPQDVLAYTFFT
SSYAIQSPFPEAAVSRIVVHTRWASNVDFDRDSSVIMAPPTENNIHLFKQ
LLNTETLSVRGANPLMFRANVLHMLLEFVLDNLYLNRHTGFSQDHTPFTE
GANLRSLPGPDAEKWYSIMYPTRMGTPNVSKICNFVASCVRNRVGRFDRA
QMMNGAMSEWVDVFETSDALTVSIRGRWMARLARMNINPTEIEWALTECA
QGYVTVTSPYAPSVNRLMPYRISNAERQISQIIRVMNIGNNATVIQPVLQ
DISVLLQRISPLQIDPTIISNTMSTQTLSPASSILGKLRPSNSDFSSFRV
ALAGWLYNGVVTTVIDDSSYPKDGGSVTSLENLWDFFILALALPLTTDPC
APVKAFMTLANMMVGFETIPMDNQIYTQSRRASAFSTPHTWPRCFMNIQL
ISPIDAPILRQWAEIIHRYWPNPSQIRYGTPNVFGSANLFTPPEVLLLPI
DHQPANVTTPTLDFTNELTNWRARVCELMKNLVDNQRYQPGWTQSLVSSM
RGTLGKLKLIKSMTPMYLQQLAPVELAVIAPMLPFPPFQVPYVRLDRDRV
PTMVGVTRQSRDTITQPALSLSTTNTTVGVPLALDARAITVALLSGKYPP
DLVTNVWYADAIYPMYADTEVFSNLQRDVITCEAVQTLVTLVAQISETQY
PVDRYLDWIPSLRASAATAATFAEWVNTSMKTAFDLSDMLLEPLLSGDPR
MTQLAIQYQQYNGRTFNVIPEMPGSVIADCVQLTAEVFNHEYNLFGIARG
DIIIGRVQSTHLWSPLAPPPDLVFDRDTPGVHIFGRDCRISFGMNGAAPM
IRDETGMMVPFEGNWIFPLALWQMNTRYFNQQFDAWIKTGELRIRIEMGA
YPYMLHYYDPRQYANAWNLTSAWLEEITPTSIPSVPFMVPISSDHDISSA
PAVQYIISTEYNDRSLFCTNSSSPQTIAGPDKHIPVERYNILTNPDAPPT
QIQLPEVVDLYNVVTRYAYETPPITAVVMGVP
3D structure
PDB7yev In situ structures of polymerase complex of mammalian reovirus illuminate RdRp activation and transcription regulation.
Chainc
Resolution3.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN c C186 H199 H203 C8 H21 H25
Gene Ontology
Molecular Function
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006370 7-methylguanosine mRNA capping
Cellular Component
GO:0019028 viral capsid
GO:0039625 viral inner capsid

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7yev, PDBe:7yev, PDBj:7yev
PDBsum7yev
PubMed36469786
UniProtC9E874

[Back to BioLiP]