Structure of PDB 7sfr Chain c

Receptor sequence
>7sfrc (length=207) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
GQKINPHGFRLGITTDWKSRWYADKQYAEYVKEDVAIRRLLSSGLERAGI
ADVEIERTRDRVRVDIHTARPGIVIGRRGTEADRIRADLEKLTGKQVQLN
ILEVKNPESQAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRV
QCSGRLGGAEMSRSEFYREGRVPLHTLRADIDYGLYEAKTTFGRIGVKVW
IYKGDIV
3D structure
PDB7sfr Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents.
Chainc
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna c G2 Q3 K4 I5 F10 I14 S154 E161 S163 R169 R172 V173 H176 L178 R179 E188 F193 G194 R195 K199 G1 Q2 K3 I4 F9 I13 S153 E160 S162 R168 R171 V172 H175 L177 R178 E187 F192 G193 R194 K198
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7sfr, PDBe:7sfr, PDBj:7sfr
PDBsum7sfr
PubMed36827973
UniProtP9WH37|RS3_MYCTU Small ribosomal subunit protein uS3 (Gene Name=rpsC)

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