Structure of PDB 7otc Chain c

Receptor sequence
>7otcc (length=206) Species: 469008 (Escherichia coli BL21(DE3)) [Search protein sequence]
GQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKAS
VSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQI
NIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKV
EVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVW
IFKGEI
3D structure
PDB7otc The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Chainc
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna c G2 Q3 K4 V5 I14 R127 G155 R156 E161 I162 A163 W167 R172 L175 H176 T177 L178 R179 Y193 V195 G197 K199 G1 Q2 K3 V4 I13 R126 G154 R155 E160 I161 A162 W166 R171 L174 H175 T176 L177 R178 Y192 V194 G196 K198
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation

View graph for
Molecular Function

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Biological Process
External links
PDB RCSB:7otc, PDBe:7otc, PDBj:7otc
PDBsum7otc
PubMed35500116
UniProtA0A140N4K1

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