Structure of PDB 5gpn Chain c

Receptor sequence
>5gpnc (length=410) Species: 9823 (Sus scrofa) [Search protein sequence]
GRHDWRLKGAQSRGDWYKTKEILLKGPDWILGEVKTSGLRGRGGAGFPTG
LKWSFMNKPSDGRPKYLVVNADEGEPGTCKDREIIRHDPHKLVEGCLVGG
RAMGARAAYIYIRGEFYNEASNLQVAIREAYEAGLIGKNACGSGYDFDVF
VVRGAGAYICGEETALIESIEGKQGKPRLKPPFPADVGVFGCPTTVANVE
TVAVSPTICRRGGAWFASFGRERNSGTKLFNISGHVNHPCTVEEEMSVPL
KELIEKHAGGVIGGWDNLLAVIPGGSSTPLIPKSVCETVLMDFDALVQAQ
TGLGTAAVIVMDRSTDIVKAIARLIEFYKHESCGQCTPCREGVDWMNKVM
ARFVKGDARPAEIDSLWEISKQIEGHTICALGDGAAWPVQGLIRHFRPEL
EERMQQFALQ
3D structure
PDB5gpn The architecture of the mammalian respirasome.
Chainc
Resolution5.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 c I205 P223 S378 C379 Q381 C382 C385 T423 I424 C425 L427 I159 P177 S332 C333 Q335 C336 C339 T377 I378 C379 L381
BS02 FMN c G87 R88 G89 K98 N116 D118 Y204 G207 E208 E209 A243 N244 G41 R42 G43 K52 N70 D72 Y158 G161 E162 E163 A197 N198
Gene Ontology
Molecular Function
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0010181 FMN binding
GO:0046872 metal ion binding
GO:0051287 NAD binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0042775 mitochondrial ATP synthesis coupled electron transport
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005829 cytosol
GO:0045271 respiratory chain complex I

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5gpn, PDBe:5gpn, PDBj:5gpn
PDBsum5gpn
PubMed27654917
UniProtA0A4X1SZP7

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