Structure of PDB 7p1n Chain bb

Receptor sequence
>7p1nbb (length=254) Species: 9606 (Homo sapiens) [Search protein sequence]
DAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQ
PWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTP
YPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVG
AFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESA
GAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHL
VGCP
3D structure
PDB7p1n A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning.
Chainbb
Resolution2.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.7: acetylcholinesterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG bb G240 G242 G236 G238
Gene Ontology
Molecular Function
GO:0004104 cholinesterase activity

View graph for
Molecular Function
External links
PDB RCSB:7p1n, PDBe:7p1n, PDBj:7p1n
PDBsum7p1n
PubMed35255209
UniProtP22303|ACES_HUMAN Acetylcholinesterase (Gene Name=ACHE)

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