Structure of PDB 9fst Chain b

Receptor sequence
>9fstb (length=195) Species: 9606,559292 [Search protein sequence]
TIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAAD
TQAIADIVQYHLELYTSQYGTPSTETAASVFKELCYENKDNLTAGIIVAG
YDDKNKGEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEET
VDFIKHSLSQAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL
3D structure
PDB9fst Structure-based design of peptide epoxyketones selectively targeting the three human immunoproteasome active sites
Chainb
Resolution2.75 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 A1IF8 b T2 D17 V20 S21 F31 K33 L45 S46 G47 A49 G128 S129 S168 T1 D16 V19 S20 F30 K32 L44 S45 G46 A48 G127 S128 S167
External links
PDB RCSB:9fst, PDBe:9fst, PDBj:9fst
PDBsum9fst
PubMed
UniProtP28065|PSB9_HUMAN Proteasome subunit beta type-9 (Gene Name=PSMB9);
P38624|PSB1_YEAST Proteasome subunit beta type-1 (Gene Name=PRE3)

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