Structure of PDB 8szn Chain b

Receptor sequence
>8sznb (length=191) Species: 487 (Neisseria meningitidis) [Search protein sequence]
LVPTVIEQSGRGERAFDIYSRLLKERIVFLVGPVTDESANLVVAQLLFLE
SENPDKDIFFYINSPGGSVTAGMSIYDTMNFIKPDVSTLCLGQAASMGAF
LLSAGEKGKRFALPNSRIMIHQPLIGGQASDIEIHARELLKIKEKLNRLM
AKHCDRDLADLERDTDRDNFMSAEEAKEYGLIDQILENRAS
3D structure
PDB8szn Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases.
Chainb
Resolution2.33 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 X3O b F54 S57 F87 F48 S51 F81
BS02 X3O b R27 L28 E31 I33 F65 Y67 F117 L119 L196 R199 R21 L22 E25 I27 F59 Y61 F111 L113 L186 R189
External links
PDB RCSB:8szn, PDBe:8szn, PDBj:8szn
PDBsum8szn
PubMed39221504
UniProtQ9JZ38|CLPP_NEIMB ATP-dependent Clp protease proteolytic subunit (Gene Name=clpP)

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