Structure of PDB 7oht Chain b

Receptor sequence

>7ohtb (length=453) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]

MQLSWKDIPTVAPANDLLDIVLNRTQRKTPTVIRPGFKITRIRAFYMRKV
KYTGEGFVEKFEDILKGFPNINDVHPFHRDLMDTLYEKNHYKISLAAISR
AKSLVEQVARDYVRLLKFGQSLFQCKQLKRAALGRMATIVKKLRDPLAYL
EQVRQHIGRLPSIDPNTRTLLICGYPNVGKSSFLRCITKSDVDVQPYAFT
TKSLYVGHFDYKYLRFQAIDTPGILDRPTEEMNNIEMQSIYAIAHLRSCV
LYFMDLSEQCGFTIEAQVKLFHSIKPLFANKSVMVVINKTDIIRPEDLDE
ERAQLLESVKEVPGVEIMTSSCQLEENVMEVRNKACEKLLASRIENKQPQ
ARDDVKRTPFIPESVKNLKKYDPEDPNRRKLARDIEAENGGAGVFNVNLK
DKYLLEDDEWKNDIMPEILDGKNVYDFLDPEIAAKLQALEEEEEKLENEG
FYN

3D structure

PDB

7oht Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.

Chain

Resolution

4.7 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	b	K6 P9 D19 I20 L22 N23 Q26 R27 K28 T31 V32 I33 R34 P35 G36 K38 R43 M47 K49 N70 I71 N72 K92 I93 L95 A96 S99 R100 S103 R110 R114 K117 F118 F123 K126 K129 R135 T138 K142 R154 Q155 R159 S162 K189 S190 Y197 F199 V206 H208 N233 G410	K6 P9 D19 I20 L22 N23 Q26 R27 K28 T31 V32 I33 R34 P35 G36 K38 R43 M47 K49 N70 I71 N72 K92 I93 L95 A96 S99 R100 S103 R110 R114 K117 F118 F123 K126 K129 R135 T138 K142 R154 Q155 R159 S162 K189 S190 Y197 F199 V206 H208 N233 G393

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding

	Biological Process
GO:0000054	ribosomal subunit export from nucleus
GO:0006364	rRNA processing
GO:0042254	ribosome biogenesis
GO:0042273	ribosomal large subunit biogenesis
GO:1902626	assembly of large subunit precursor of preribosome

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0030687	preribosome, large subunit precursor

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Molecular Function

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Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:7oht, PDBe:7oht, PDBj:7oht
PDBsum	7oht
PubMed	34813592
UniProt	Q02892\|NOG1_YEAST Nucleolar GTP-binding protein 1 (Gene Name=NOG1)

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