Structure of PDB 7o37 Chain b

Receptor sequence
>7o37b (length=227) Species: 10090 (Mus musculus) [Search protein sequence]
MAYPFQLGLQDATSPIMEELMNFHDHTLMIVFLISSLVLYIISLMLTTKL
THTSTMDAQEVETIWTILPAVILIMIALPSLRILYMMDEINNPVLTVKTM
GHQWYWSYEYTDYEDLCFDSYMIPTNDLKPGELRLLEVDNRVVLPMELPI
RMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATVTSNRPGLFYGQCSEIC
GSNHSFMPIVLEMVPLKYFENWSASMI
3D structure
PDB7o37 Structure and assembly of the mammalian mitochondrial supercomplex CIII 2 CIV.
Chainb
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.9: cytochrome-c oxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEA b I34 P69 I72 L73 I34 P69 I72 L73
BS02 CUA b H161 C196 C200 H204 M207 H161 C196 C200 H204 M207
Gene Ontology
Molecular Function
GO:0004129 cytochrome-c oxidase activity
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0001666 response to hypoxia
GO:0007595 lactation
GO:0022900 electron transport chain
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0031966 mitochondrial membrane
GO:0045277 respiratory chain complex IV

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Molecular Function
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Cellular Component
External links
PDB RCSB:7o37, PDBe:7o37, PDBj:7o37
PDBsum7o37
PubMed34616041
UniProtP00405|COX2_MOUSE Cytochrome c oxidase subunit 2 (Gene Name=Mtco2)

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