Structure of PDB 7ezj Chain b

Receptor sequence
>7ezjb (length=199) Species: 9606 (Homo sapiens) [Search protein sequence]
HEFIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPI
QIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPA
SHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSS
CVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYR
3D structure
PDB7ezj Deciphering the mechanism of p73 recognition of p53 response elements using the crystal structure of p73-DNA complexes and computational studies.
Chainb
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna b S261 R293 A296 R300 S150 R182 A185 R189
BS02 dna b A137 K138 A26 K27
BS03 ZN b C194 H197 C258 C262 C83 H86 C147 C151
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ezj, PDBe:7ezj, PDBj:7ezj
PDBsum7ezj
PubMed35217090
UniProtO15350|P73_HUMAN Tumor protein p73 (Gene Name=TP73)

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