Structure of PDB 7dts Chain b

Receptor sequence
>7dtsb (length=680) Species: 9823 (Sus scrofa) [Search protein sequence]
LEEMLTQAVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDL
VALLLKHGADPCLRKRNGATPFIIAGITGNVRLLQLLLPNVEDVNECDVN
GFTAFMEAAVYGRVEALRFLYENGADVNMHRKTKQDQERIRKGGATALMD
AAEKGHVGVVTILLHAMKAEVDARDNMGRNALVYALLNPDDGKAKAITRL
LLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIEVNDTDREGK
TALLLAVELRLEEIAKLLCHRGASTNCGDLVAIARRNYDSDLVKFLRLHP
PAENWKPQSSRWGEALKHLHRIWRPMIGKLKIFIDEEYKIADTAEGGIYL
GLYEDQEVAVKRFSEGSTRGQQEVSCLQSSRANDNVVTFYGSESDGSCLH
VCLALCEYTLQEHLANHRGDAVPNEEDESARNILSSLFKAIGELHRSGYS
HQDLQPQNILIDSKNGTFLADFDKSIKWAEDPQKIKRDLEALGLLVLYVV
KKGDISFETLKNQSFEEVIQGSPDEETRDLIHHLFHPGDNVEDRLSSLLA
HPFFWSWESRYRTLRDVGNESDIKTRNQNSRILQLLQPGTLSTSFAQWTT
KIDSFVMEEMNAYNLYQDTLGDLLKFIRNLGEHINEQKNKKMKSIIGEPS
QYFQEKFPDLVMYVYTKLQNTEYMKHFPKT
3D structure
PDB7dts Identification of Small Molecule Inhibitors of RNase L by Fragment-Based Drug Discovery
Chainb
Resolution2.63 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 25A b R307 R308 Y310 R353 R285 R286 Y288 R324
BS02 25A b W56 W58 Q66 K87 N89 N122 F124 E129 Y133 K164 W34 W36 Q44 K65 N67 N100 F102 E107 Y111 K142
BS03 27K b I377 A388 L434 C435 E436 Y437 L489 A499 D500 I348 A359 L405 C406 E407 Y408 L460 A470 D471
Gene Ontology
Molecular Function
GO:0004540 RNA nuclease activity
GO:0004672 protein kinase activity
GO:0005524 ATP binding
GO:0046872 metal ion binding
Biological Process
GO:0006397 mRNA processing
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7dts, PDBe:7dts, PDBj:7dts
PDBsum7dts
PubMed
UniProtA5H025

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