Structure of PDB 6cb1 Chain b

Receptor sequence
>6cb1b (length=242) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence]
QRTLLISSRGVNYRHRHLIQDLSGLLPHSRKEPKLDTKKDLQQLNEIAEL
YNCNNVLFFEARKHQDLYLWLSKPPNGPTIKFYIQNLHTMDEAAAAAAAA
AGSRPVLSFDQRFESSPHYQLIKELLVHNFGVPPAAAAAAAAADHVMSFS
IVDDKIWVRTYESLVEIGPRFVMTVILILEGSFGGPKIYENKQYVSPNVV
RAQIKQQAAEEAKSRAEAAVERKIKRRENVLAADPLSNDALF
3D structure
PDB6cb1 Modular assembly of the nucleolar pre-60S ribosomal subunit.
Chainb
Resolution4.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna b V41 P63 R92 K93 G232 G233 P234 V11 P33 R62 K63 G184 G185 P186
BS02 peptide b N82 P105 N52 P75
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
GO:0042134 rRNA primary transcript binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0000464 endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000465 exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6cb1, PDBe:6cb1, PDBj:6cb1
PDBsum6cb1
PubMed29512650
UniProtQ08235|BRX1_YEAST Ribosome biogenesis protein BRX1 (Gene Name=BRX1)

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