Structure of PDB 5yj1 Chain b

Receptor sequence
>5yj1b (length=93) Species: 10090 (Mus musculus) [Search protein sequence]
GPTSLCCKQCQETEITTKNEIFSLSHETLTVYKASNLNLIGRPSTVHSWF
PGYAWTIAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLP
3D structure
PDB5yj1 Structural basis of thalidomide enantiomer binding to cereblon
Chainb
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 6EL b H381 W383 W389 W403 F405 H47 W49 W55 W69 F71
BS02 ZN b C326 C329 C394 C397 C7 C10 C60 C63
External links
PDB RCSB:5yj1, PDBe:5yj1, PDBj:5yj1
PDBsum5yj1
PubMed29358579
UniProtQ8C7D2|CRBN_MOUSE Protein cereblon (Gene Name=Crbn)

[Back to BioLiP]