Structure of PDB 8pw5 Chain a

Receptor sequence
>8pw5a (length=514) Species: 10090 (Mus musculus) [Search protein sequence]
MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSILIRAELGQPGALLGD
DQIYNVIVTAHAFVMIFFMVMPMMIGGFGNWLVPLMIGAPDMAFPRMNNM
SFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSL
HLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLITAVLLLLSLP
VLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPG
FGIISHVVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGLDVD
TRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMLWALGFIFLFTV
GGLTGIVLSNSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMAGFVHWFPLF
SGFTLDDTWAKAHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTTW
NTVSSMGSFISLTAVLIMIFMIWEAFASKREVMSVSYASTNLEWLHGCPP
PYHTFEEPTYVKVK
3D structure
PDB8pw5 SCAF1 drives the compositional diversity of mammalian respirasomes.
Chaina
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.9: cytochrome-c oxidase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0004129 cytochrome-c oxidase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0001666 response to hypoxia
GO:0006119 oxidative phosphorylation
GO:0006979 response to oxidative stress
GO:0009060 aerobic respiration
GO:0021549 cerebellum development
GO:0046688 response to copper ion
GO:0051602 response to electrical stimulus
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0031966 mitochondrial membrane
GO:0045277 respiratory chain complex IV

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8pw5, PDBe:8pw5, PDBj:8pw5
PDBsum8pw5
PubMed38575788
UniProtP00397|COX1_MOUSE Cytochrome c oxidase subunit 1 (Gene Name=Mtco1)

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