Structure of PDB 8ow1 Chain a

Receptor sequence
>8ow1a (length=97) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
TPSELALYEIRKYQRSTDLLISKIPFARLVKEVTDEFTTKDQDLRWQSMA
IMALQEASEAYLVGLLEHTNLLALHAKRITIMKKDMQLARRIRGQFI
3D structure
PDB8ow1 Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Chaina
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna a R177 W178 R45 W46
BS02 dna a P134 S154 K155 I156 P157 R160 P2 S22 K23 I24 P25 R28
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0019237 centromeric DNA binding
GO:0030527 structural constituent of chromatin
GO:0043565 sequence-specific DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0000070 mitotic sister chromatid segregation
GO:0000278 mitotic cell cycle
GO:0009303 rRNA transcription
GO:0030543 2-micrometer plasmid partitioning
GO:0051382 kinetochore assembly
GO:0061644 protein localization to CENP-A containing chromatin
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000779 condensed chromosome, centromeric region
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005729 2-micrometer circle DNA
GO:0005777 peroxisome
GO:0032991 protein-containing complex
GO:0043505 CENP-A containing nucleosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ow1, PDBe:8ow1, PDBj:8ow1
PDBsum8ow1
PubMed37506202
UniProtP36012|CENPA_YEAST Histone H3-like centromeric protein CSE4 (Gene Name=CSE4)

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